Radix Angelicae Pubescentis (R.A.P.) is mainly produced in Sichuan, Hubei, Anhui and other provinces in China. Usually its excavation takes place early spring or late fall. It is common to remove the fibrous roots and sediment, half dried above the heated mud. They were piled for 2 to 3 days, then heated to dry absolutely when they become soft.
Columbianetin, Columbianetin acetate, Columbiadin, osthol, isoimperatorin, bergapten, xanthotoxin, Columbianetin-β-D-glucopyranosid, etc are the main compounds from the ethanol extracts of the R.A.
