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Pyrroloquinoline Quineone/PQQ

Product Name: Pyrroloquinoline Quineone
Botanical Source:
Part Used:
Specification: Molecular Formula:C14H4N2Na2O8 CAS Number:122628-50-6 Molecular Weight:374.17 Appearance: Reddish brown powder Melting Point: >300℃ (decomposed during the assay) Solubility: Water-soluble (3g/L at 25℃) Stability: Stable for at least 24 months.
Appearance: Reddish brown powder

Product Name:PQQ

Chemical Name:Pyrroloquinoline Quinone Disodium Salt (PQQ Na2)
Molecular Formula:C14H4N2Na2O8 
CAS Number:122628-50-6
Molecular Weight:374.17
Appearance: Reddish brown powder
Melting Point: >300℃ (decomposed during the assay)
Solubility: Water-soluble (3g/L at 25)

Stability: Stable for at least 24 months.


Cognitive Support
Prevents cognitive decline (memory loss, learning difficulty, etc.) 
due to age, stroke or neurodegenerative disorders.
Protects and restores damaged brain and nerve cells.
Cardiovascular Support
Supports energy (ATP) metabolism by the mitochondria.
Provides powerful antioxidant protection from damaging free 
Liver Metabolism Support

Rescue acute and chromic liver injury caused by various factors.

PQQ is Widely Distributed in Daily Life

The PQQ content of food products listed is substantially lower than the content of supplemented PQQ (10-20mg) and food ingestion is unlikely to replicate the effects of supplementatio n due to the magnitude of difference




PQQ(ng/g or ml)



broad Bean  17.8±6.8
Green Tea 29.6±12.9
Soy bean 9.3±3.8 Oolong Tea  27.7±1.9
Patato    116.6±7.3



Sweet Potato

13.3±3.7 Wine  5.8±2.7


34.2±11.6 Saka 3.7±1.4


16.8±2.8 Fermernted food and others

Green Pepper

28.2±13.7 Natto  61.0±31.3


21.9±6.2 Sauce 16.7±3.3


9.2±1.8 Tofu 24.4±12.5
Apple 6.1±1.4 Breast Milk  140-180*

Proven Benefits of PQQ (Human and In Vivo)

PQQ Decreases Inflammation Biomarkers and Free Radicals? 

Healthy humans who took 20mg of PQQ resulted in significant decreases chronic inflammation biomarkers of C-reactive protein (by45% after 3 weeks) and IL-6.

PQQ Creates New Mitochondria and Enhance Mitochondrial Function

Stimulate mitochondrial biogenesis are linked to many health benefits such increased longevity, improved energy utilization, and protection from free radicals.

By increasing cellular metabolism it favorably affects blood pressure, cholesterol and triglyceride breakdown, and the onset of obesity .

Mice and rats fed diets lacking in pyrroloquinoline quinone (PQQ) have reduced mitochondrial content.

PQQ Improves Memory and Reasoning

A study with middle ages and elderly people found PQQ + CoQ10 led to a significant increase in performance in the Stroop test (measures reasoning) and reaction tests.

PQQ Improves Brain Function By Increasing Nerve Growth Factor and Schwann Cells

PQQ is Neuroprotective Against Alzheimer’s, Parkinson’s and Cognitive Injuries

PQQ Improves Sleep, Mood, and Fatigue

One open-label human study conducted with 20mg PQQ for 8 weeks in 17 persons with fatigue or sleep-impairing disorder noted that PQQ was able to significantly improve sleep quality, with improvements in sleep duration and quality appearing at the first testing period after 4 weeks. It also led to a decrease in the time it took to fall asleep but required 8 weeks to reach significance.

PQQ Protects Brain and Heart Against Stroke

PQQ administration reduces the size of damaged areas in animal models of acute brain stroke and heart attack.

PQQ Decreases Insulin Resistance

PQQ alleviates fat-induced insulin resistance by increasing mitochondrial biogenesis in muscle cells, similar to exercise

PQQ Slows Down the Progression of Osteoarthritis by Inhibiting Nitric Oxide Production and Metalloproteinase Synthesis

PQQ Improved Dry Skin Condition in Women


A novel antioxidant
PQQ protects human body and organs against aging.
PQQ is a small quinone molecule which has the ability to be a REDOX agent,capable 
of reducing oxidants (an antioxidant effect) and then being recycled by glutathione 
back into an active form.
It appears to be quite stable as it can undergo 20-thousand cycles before being used 
up,and it is novel since it associates with protein structures inside the cell
Protects and increases the functionality of existing 
mitochondria, and also promotes the generation of new 
mitochondria (Mitochondrial Biogenesis).
Increased mitochondria = increased energy production.
Stimulates production of Nerve Growth Factor (NGF)
NGF triggers growth of nerve cells to repair damaged nerves from stroke or other injury.



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1.Leading natural ingredients supplier with nearly 20 years' experience.

2.Awarded FSSC22000,ISO9001-2000,ECO CERT, HACCP, Halal, Kosher, Organic Certifications.

3.Clean workshop and manufacture base operation is controlled according to the GMP standards strictly.

4.Quality control with testing equipment: AAS, MICROBE, HPLC,TLC,GC,UV,PPSL (irradiation test).

5.24 hours online and multilingual services to ensure timely responds.

6.30 days unconditional refund if unqualified.

7.Professional logistics (DHL, FedEx, EMS, By Air, By Sea), fast & safe shipment.

8.Professional R&D team and strong R&D strength.

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Hunan Huakang Biotech Inc., was founded in 2003, specializing in the processing and production of extracting active ingredients from natural plants, tablets, capsules, confectionery punches.
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