Radix Isatidis , as the Traditional Chinese Medicine (TCM), is a kind of dried root of the plant Isatidis indigotica Fort (family Cruciferae), and is officially listed in the Chinese Pharmacopoeia. It is mainly distributed in Hebei, JiangXi, Zhejiang,Fujian, Anhui and Gansu provinces in China. It has been used as a medicinal plant for more than 2000 years from <ShenNong materia medica>, a famous ancient Chinese medicinal literary and Radix Isatidis has been widely used to anti-virus, anti-bacterial, anti-endotoxic, antiinflammatory, and immune regulatory effects. Because the chemical constituents and antibacterial effect of Radix Isatidis remain uncertain, the reasons for its actions have remained a puzzle for a long time. Some researchers considered that the extract of Radix Isatidis had high anti-virus effects.