Momordica charantia is a potential herbal alternative for blood sugar management, particularly in non-insulin dependent diabetes.Momordica charantia (bitter melon) is a proven hypoglycemic agent. One of the active principles responsible for this action is charantin, which is composed of a mixture of beta-sitosterol-beta-D-glucoside and 5,25 stigmadien-3-beta-ol glycoside.
The plant Momordica charantia belongs to the family cucuritaceae and is commonly known as bitter melon. Bitter melon grows in tropical and subtropic areas, including parts of East Africa, Asia, the Caribbean, and South America, where it is used as a food as well as a medicine. It produces beautiful flowers and prickly fruit. The fruit of this plant lives up to its nameit tastes bitter. Although the seeds, leaves, and vines of bitter melon have all been used, the fruit is the safest and most prevalent part of the plant used medicinally. The juice of the leaves and fruit or seeds is used as an anthelmintic. In Brazil, the dose for anthelmintic use is two or three seeds. The immature fruit of M. Charantia tastes bitter due to the cucurbitacius. Cucurbitacius is comprised of a group of triterpenes including momordicosides, A-E, K, L, and momardicius I, II and III. The roots and fruit are used as an abortifacient.