Sophora Japonica Extract (Quercetin)

Sophora Japonica Extract (Quercetin)

Sophora Japonica L. is a perennial deciduous woody plant belonging to the genus Sophora in the family Leguminosae. It is native to China and then became widely spread and cultivated throughout Asian and European countries. Sophora Japonica is often cultivated for its ornamental value in landscaping, to purify the air, or to improve soil quality. Moreover, it is also an important economical plant with edible and medicinal properties. The flowers or flower buds of Sophora Japonica are not only processed into dishes, dumplings, cakes, and beverages; their extracts can also be used as a preservative in sausages, a color or flavor enhancer in rice wine, a synergist in low-fat yogurt, and an antioxidant in edible films .

The flowers, fruits, bark, branches, and leaves of Sophora Japonica have been used in traditional medicines over the past 2000 years for heat clearance, detoxification, blood pressure reduction, and bleeding control. Modern pharmacological research reports that Sophora Japonica exhibits various beneficial biological effects, such as antibacterial, antioxidant, anti-inflammatory, anticancer, and cardioprotective activities. The health benefits conferred by these processes are related to the plant's phytochemical constituents, including flavonoids, triterpenoids, polysaccharides, essential oils, fatty acids, amino acids, and trace elements . Among these bioactive compounds, flavonoids are abundant in all parts of Sophora Japonica.

In addition to being consumed as a ready-to-eat food, Sophora Japonica is generally processed to obtain extracts and bioactive compounds . These compounds are widely used in food, pharmaceuticals, and cosmetics.

Extraction is the first step for recovering target extracts from the plant matrix. Different extraction techniques are used to obtain bioactive compounds from Sophora Japonica , such as solid–liquid extraction (SLE), ultrasonic-assisted extraction (UAE), microwave-assisted extraction (MAE), infrared-assisted extraction (IAE), pressure-enhanced solid–liquid extraction (PSE), supercritical fluid extraction (SFE), and ionic liquid (IL)-based or deep eutectic solvent (DES)-based extraction.

Following extraction, numerous separation methods are available to purify the target compounds from the Sophora Japonica extracts, including column chromatography, preparative liquid chromatography (PLC), countercurrent chromatography (CCC), molecular imprinting technology (MIT), and crystallization .

Quercetin is a kind of flavonoid compound which is widely found in Sophora Japonica L.. Quercetin has been widely reported for its excellent biological properties such as antibacterial, antioxidant, gut health improver, growth promoter, and immunomodulatory.

We Hunan Huakang Biotech Inc., offerring Sophora Japonica Extract with:

Quercetin is a crystalline, yellow material which is entirely insoluble in cold water, soluble in alcohol and lipids, and marginally soluble in hot water and has a bitter taste. It is an aglucone or aglycon that does not include any carbohydrate molecules in its structure, and it gives a range of flowers great colors. Free radicals react with other substances rapidly in order to obtain their electrons and become stable. An attack causes a molecule to lose an electron and turn into a free radical, which sets off a series of events that disturb living cells. From the literature, the hydroxyl groups at the A and B rings’ 3, 5, 7, 3’ and 4’, the double bond between the second and third carbons, and the carbonyl group on the fourth carbon were verified to have a major part in the antioxidant capabilities of quercetin. It also exhibits a variety of intriguing treatments for different health issues such as anticancer activity, antiallergic activity, anti-diabetes activity, anti-obesity activity, anti-hyperuricemia and gouty arthritis, etc. The most important impact of quercetin is its ability to inhibit the spread of certain cancers including those of the breast, cervical, lung, colon, prostate, and liver. The capacity to block enzymes that activate carcinogens and diverse processes involving cellular signaling are used to exert the aforementioned anticancer effects.