The Powerful Antioxidant: Alpha Lipoic Acid

Alpha lipoic acid (ALA) (often called a-lipoic acid), also known as thioctic acid, is a naturally occurring organosulfur compound that is produced by plants and animals, including humans.

Alpha lipoic acid is covalently bound to certain proteins, which function as part of essential mitochondrial multienzyme complexes involved in energy and amino acid metabolism (see Biological Activities). In addition to the physiological functions of protein-bound lipoic acid, there is increasing scientific and medical interest in potential therapeutic uses of pharmacological doses of free (unbound) lipoic acid.

Lipoic acid contains two thiol (sulfur) groups, which may be oxidized or reduced; dihydrolipoic acid is the reduced form of lipoic acid. Lipoic acid also contains an asymmetric carbon, which means that lipoic acid can exist as one of two possible optical isomers, also called enantiomers. These enantiomers are mirror images of each other: R-lipoic acid and S-lipoic acid. Only the R-enantiomer is endogenously synthesized and covalently bound to protein. R-lipoic acid occurs naturally in food (see Food sources). Free (unbound) lipoic acid supplements may contain either R-lipoic acid or a 50:50 (racemic) mixture of R-lipoic acid and S-lipoic acid (see Supplements).

Alpha lipoic acid (ALA) is an antioxidant made by the body. It is found in every cell, where it helps turn glucose into energy. Antioxidants attack "free radicals," waste products created when the body turns food into energy. Free radicals cause harmful chemical reactions that can damage cells, making it harder for the body to fight off infections. Alpha lipoic acid (ALA) protect against damage to the body's cells.

There are food sources of ALA such as yeast, organ meats like liver and heart, spinach, broccoli, and potatoes. However, ALA from food does not appear to produce a noticeable increase in the level of free ALA in the body.

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Alpha lipoic acid (ALA) is UNIQUE, because it is Both Water and Fat-Soluble, meaning it can work in all parts of the body, including the inside and outside of cells. It is able to regenerate other antioxidants, such as vitamins C and E, helping them to continue their role in fighting free radicals and protecting cells from damage.

Alpha lipoic acid (ALA) has been studied for its potential health benefits, including its ability to reduce inflammation, improve insulin sensitivity, and enhance the body's natural detoxification processes. It may also have neuroprotective properties and could potentially help with conditions such as diabetic neuropathy and age-related cognitive decline.

Moreover, ALA has gained popularity as a dietary supplement for its potential anti-aging effects and overall health benefits. It is available in easy-to-consume capsule or tablet form, making it convenient to incorporate into your daily routine.

It's important to note that while ALA is generally considered safe for most people when taken in appropriate doses, it can interact with certain medications and may not be suitable for everyone. As with any supplement, it's recommended to consult with a healthcare professional before adding ALA to your routine.