Artemisia Annua Extract Artemisinin 99% Anti-malarial And Health Applications

Description:

Artemisinin is an organic compound with a molecular formula of C15H22O5 and a relative molecular mass of 282.34.

Artemisinin is a colorless needle-shaped crystal, easily soluble in chloroform, acetone, ethyl acetate and benzene, soluble in ethanol and ether, slightly soluble in cold petroleum ether, and almost insoluble in water. Because it has a special peroxy group, it is thermally unstable and susceptible to decomposition under the influence of moisture, heat and reducing substances.

Artemisinin is a drug derived from the Asian plant Artemisia annua. This aromatic plant has fern-like leaves and yellow flowers.

For more than 2,000 years, it has been used to treat fevers. It’s also an effective treatment for malaria.

Artemisinin is extracted from the plant Artemisia annua, an herb used in traditional Chinese medicine.

Artemisinin and its derivatives are both sesquiterpene lactones with unusual peroxide bridges. This endoperoxide 1,2,4-trioxane ring is responsible for its antimalarial properties. Few other natural compounds with such peroxide bridges are known.

Artemisinin and its derivatives have been used to treat malaria and parasitic (worm) infections. Their advantage over other drugs is that they kill the parasite more quickly and kill all the life cycle stages of the parasite.

Artemisinin and its semisynthetic derivatives are a group of drugs used in the treatment of malaria due to Plasmodium falciparum.It was discovered in 1972 by Tu Youyou, who shared the 2015 Nobel Prize in Physiology or Medicine for her discovery. Artemisinin-based combination therapies (ACTs) are now standard treatment worldwide for P. falciparum malaria as well as malaria due to other species of Plasmodium.Artemisinin is extracted from the plant Artemisia annua (sweet wormwood) a herb employed in Chinese traditional medicine. A precursor compound can be produced using a genetically engineered yeast, which is much more efficient than using the plant.

Artemisinin and its derivatives are all sesquiterpene lactones containing an unusual peroxide bridge. This endoperoxide 1,2,4-trioxane ring is responsible for their antimalarial properties. Few other natural compounds with such a peroxide bridge are known.

Artemisinin and its derivatives have been used for the treatment of malarial and parasitic worm (helminth) infections. Advantages of such treatments over other anti-parasitics include faster parasite elimination and broader efficacy across the parasite life-cycle; disadvantages include their low bioavailability, poor pharmacokinetic properties, and high cost. Moreover, use of the drug by itself as a monotherapy is explicitly discouraged by the World Health Organization, as there have been signs that malarial parasites are developing resistance to the drug. Combination therapies, featuring artemisinin or its derivatives alongside some other antimalarial drug, constitute the contemporary standard-of-care treatment regimen for malaria.